Hypoxic-ischemic brain injury: Pathophysiology, neuropathology and mechanisms
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چکیده
منابع مشابه
Hypoxic-ischemic brain injury: pathophysiology, neuropathology and mechanisms.
Hypoxic-ischemic brain injury is a well known consequence of cardiac arrest. Variable injuries can occur with purely hypoxic or histotoxic insults such as asphyxiation and carbon monoxide poisoning. The injury may happen at the time of the insult, but there may also be continued damage after circulation and oxygenation are reestablished. The nature and extent of the damage appears to depend on ...
متن کاملPathophysiology and Neuroprotective Strategies in Hypoxic-Ischemic Brain Injury and Stroke
Hypoxic-ischemic brain injury and stroke are closely related and devastating conditions that can affect individuals of all ages.[...].
متن کاملHypoxic-Ischemic Brain Injury in Piglets
Background and Purpose: The excitatory amino acid inhibitor MK-801 has been shown in many animals species to protect against hypoxic-ischemic brain injury. We sought to determine whether hypoxic-ischemic injury to the newborn pig's brain could be prevented by the use of MK-801. Methods: Hypoxic-ischemic injury to the brain was induced in forty 0-3-day-old piglets. They were randomized to receiv...
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Hypoxic ischemic brain injury (HIBI) after cardiac arrest (CA) is a leading cause of mortality and long-term neurologic disability in survivors. The pathophysiology of HIBI encompasses a heterogeneous cascade that culminates in secondary brain injury and neuronal cell death. This begins with primary injury to the brain caused by the immediate cessation of cerebral blood flow following CA. There...
متن کاملNeonatal Hypoxic-Ischemic Brain Injury: Mechanisms and Strategies for prevention and
Most infants affected by hypoxic-ischemic (H-I) brain injury do not require surgical intervention. However, some of these infants as well as infants with certain congenital anomalies that place them at risk for H-I brain injury will present for surgical intervention. The incidence of H-I injury is estimated to be between 1 and 6 per 1000 live term newborns (Ferriero, 2004). Neonatal hypoxic-isc...
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ژورنال
عنوان ژورنال: NeuroRehabilitation
سال: 2010
ISSN: 1053-8135,1878-6448
DOI: 10.3233/nre-2010-0531